KMID : 0604520200460020119
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Journal of the Society of Cosmetic Scientists of Korea 2020 Volume.46 No. 2 p.119 ~ p.131
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Relaxing Effect of Evening Primrose Root on Skin Irritation Caused by Particulate Matter in Subway Tunnel
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Shin Myeong-Geol
Park Eul-Yong Park Duck-Shin Kim Chong-Tai
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Abstract
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If human skin is exposed to high concentrations of particulate matter (PM2.5 and PM10) for a long time in the outdoor environment such as subway tunnel, it will be adversely affected. In particular, fine particles can damage the skin, causing inflammation and allergic reactions. This study investigated the ability of evening primrose root (EEPR) extract to suppress the skin damages caused by the fine particles. PM was collected from a subway tunnel, where high concentrations have been reported per day over the course of a study. The EEPR had higher antioxidant activity than that of control g roup (62.6%). The mixture o f EEPR and PM inhibited the production of n itric oxide (NO), thereby alleviating skin inflammation caused by fine particle dust. EEPR had weaker cytotoxic activity than the positive control.
When cells were exposed to particulate-type dust (PM10), the levels of free radicals were decreased with the increased concentrations of the extract (5, 10, 20 ¥ìg/mL). While at the same time more effective than positive controls. Therefore, this study proved that the Moonlight flower root extract can be used as a cosmetic material for skin by providing an effect to alleviate skin damage caused by fine particle-type dust.
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KEYWORD
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evening primrose, skin irritation, particulate matter, inflammation, cosmetic
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